Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 5/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1695340 | 0.83 | — | — | |
| SCHEMBL21813741 | 0.83 | — | — | |
| SCHEMBL21813769 | 0.83 | — | — | |
| SCHEMBL17493720 | 0.79 | CA12 (0.58) | EPHX2CA12CA1CA2MMP2 | |
| SCHEMBL13195814 | 0.78 | CA12 (0.61) | EPHX2CA12CA1CA2MMP2 | |
| SCHEMBL10939331 | 0.78 | CA12 (0.61) | EPHX2CA12CA1CA2MMP2 | |
| SCHEMBL13195837 | 0.78 | CA12 (0.61) | EPHX2CA12CA1CA2MMP2 | |
| SCHEMBL17981977 | 0.76 | BRD4 (0.35) | EPHX2SMYD3 | |
| SCHEMBL3501623 | 0.76 | EPHX2 (0.46) | EPHX2CA12CA1CA2MMP2 | |
| SCHEMBL3501619 | 0.76 | EPHX2 (0.46) | EPHX2CA12CA1CA2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515724-B1 | MITOTIC KINESIN INHIBITORS | MERCK & CO INC (US) | 2009-10-21 | — | — | EP | claimed |