Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 18/20 | 0.85 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1373040 | 0.92 | HRH3 (1.00) | HRH3HTR3A | |
| SCHEMBL1374936 | 0.92 | HRH3 (1.00) | HRH3HTR3A | |
| SCHEMBL1373037 | 0.92 | HRH3 (1.00) | HRH3HTR3A | |
| SCHEMBL12003271 | 0.89 | HRH3 (0.88) | HRH3HTR3AADORA1 | |
| SCHEMBL1375992 | 0.87 | HRH3 (1.00) | HRH3HTR3A | |
| SCHEMBL1373208 | 0.87 | HRH3 (1.00) | HRH3HTR3A | |
| SCHEMBL1375367 | 0.81 | HRH3 (1.00) | HRH3ADORA1 | |
| SCHEMBL1373388 | 0.81 | HRH3 (1.00) | HRH3ADORA1 | |
| SCHEMBL1376250 | 0.80 | HRH3 (0.78) | HRH3ADORA1 | |
| SCHEMBL11986853 | 0.80 | HRH3 (0.78) | HRH3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069312-A2 | PYRIDIZINONE DERIVATIVES | Cephalon, Inc. (US) | 2009-06-17 | — | — | EP | claimed |
| WO-2008013838-A2 | PYRIDIZINONE DERIVATIVES | CEPHALON, INC. (US) | 2008-01-31 | — | — | WO | claimed |