Sugi Predict

Sugi Predict / Compounds / SCHEMBL4064475

SCHEMBL4064475

SCHEMBL4064475

CCc1cccc(CC)c1/N=C1/c2cc([N+](=O)[O-])ccc2-c2c1cc([N+](=O)[O-])cc2[N+](=O)[O-]

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSP90AA1 P07900 3/20 0.65
▸ HPRT1 P00492 1/20 0.46
▸ MAPT P10636 4/20 0.41
▸ MEN1 O00255 3/20 0.41
▸ KMT2A Q03164 3/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ MCL1 Q07820 1/20 0.41
▸ POLB P06746 1/20 0.39
▸ TDP1 Q9NUW8 2/20 0.38
▸ MAPK1 P28482 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ CDK5 Q00535 1/20 0.38
▸ CDK5R1 Q15078 1/20 0.38
▸ NCOA1 Q15788 1/20 0.38
▸ NCOA3 Q9Y6Q9 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.36
▸ CYP1A2 P05177 1/20 0.36
▸ RORC P51449 1/20 0.35
▸ PTPRC P08575 3/20 0.35
▸ S100A4 P26447 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8575991 0.93 HSP90AA1 (0.64) HSP90AA1HPRT1MAPTMEN1KMT2A
SCHEMBL8573732 0.90 HSP90AA1 (0.53) HSP90AA1HPRT1MAPTMEN1KMT2A
SCHEMBL8573077 0.84 HSP90AA1 (0.52) HSP90AA1HPRT1MAPTMEN1KMT2A
SCHEMBL8580895 0.81 HSP90AA1 (0.68) HSP90AA1HPRT1MAPTMEN1KMT2A
SCHEMBL8570399 0.81 HSP90AA1 (0.53) HSP90AA1HPRT1MAPTMEN1KMT2A
SCHEMBL11694193 0.81 HSP90AA1 (0.82) HSP90AA1HPRT1MAPTMEN1KMT2A
SCHEMBL11694187 0.81 HSP90AA1 (0.82) HSP90AA1HPRT1MAPTMEN1KMT2A
SCHEMBL8574311 0.79 HSP90AA1 (0.62) HSP90AA1HPRT1MAPTMEN1KMT2A
SCHEMBL11694416 0.79 HSP90AA1 (0.76) HSP90AA1HPRT1MAPTMEN1KMT2A
SCHEMBL11694409 0.79 HSP90AA1 (0.76) HSP90AA1HPRT1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8632931-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2014-01-21 — — US disclosed
US-8632931-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2014-01-21 — — US disclosed
US-8524429-B2 — — 2013-09-03 — — US disclosed
US-8524429-B2 — — 2013-09-03 — — US disclosed
US-8507162-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2013-08-13 — — US disclosed
US-8507162-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2013-08-13 — — US disclosed
EP-2447781-B1 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KK (JP) 2013-01-16 — — EP disclosed
US-20120107735-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2012-05-03 — — US disclosed
US-20120107735-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2012-05-03 — — US disclosed
US-20110143273-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2011-06-16 — — US disclosed
US-20110143273-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2011-06-16 — — US disclosed
EP-2317391-A1 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus Canon Kabushiki Kaisha (JP) 2011-05-04 — — EP disclosed