SCHEMBL4064478

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13702959	1.00	MAPK14 (0.47)	MAPK14NPSR1RXFP1ABCB1POLB
	SCHEMBL4069015	0.93	MAPK14 (0.52)	MAPK14NPSR1RXFP1HKDC1PTGS1
	SCHEMBL27630502	0.85	MAPK14 (0.45)	MAPK14MAPK13MAPK12MAPK11
	SCHEMBL4060643	0.80	MAPK14 (0.49)	MAPK14SMN1; SMN2TP53KDM4EALDH1A1
	SCHEMBL4068837	0.77	MAPK14 (0.52)	MAPK14MAPK13MAPK12MAPK11
	SCHEMBL23182197	0.71	NPSR1 (0.49)	MAPK14NPSR1RXFP1SMN1; SMN2HTT
	SCHEMBL13096332	0.69	KDM4E (0.52)	NPSR1RXFP1SMN1; SMN2HTTKMT2A
	SCHEMBL4290818	0.69	CYP17A1 (0.42)	MAPK14SMN1; SMN2TSHRALDH1A1NPC1
	SCHEMBL24465924	0.69	PIK3CA (0.48)	MAPK14NPSR1RXFP1SMN1; SMN2HTT
	SCHEMBL8040091	0.67	CA12 (0.52)	NPSR1SMN1; SMN2TSHRHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.