Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520801 | 0.81 | KMT2A (0.64) | KMT2AKDM4ELMNAPOLBMEN1 | |
| SCHEMBL11193929 | 0.78 | HDAC6 (0.53) | APEX1KMT2AKDM4ELMNAHSD17B10 | |
| SCHEMBL17933571 | 0.76 | HDAC6 (0.72) | KMT2AKDM4ELMNAHDAC6POLB | |
| SCHEMBL3588204 | 0.72 | APEX1 (0.75) | APEX1KMT2AKDM4ELMNAHSD17B10 | |
| SCHEMBL27983763 | 0.71 | APEX1 (0.73) | APEX1KMT2AKDM4ELMNAHSD17B10 | |
| SCHEMBL10880355 | 0.71 | POLB (0.58) | KMT2AKDM4ELMNAHSD17B10POLB | |
| SCHEMBL18955291 | 0.71 | APEX1 (0.73) | APEX1KMT2AKDM4EHSD17B10POLB | |
| SCHEMBL31596375 | 0.71 | APEX1 (0.73) | APEX1KMT2AKDM4EHSD17B10POLB | |
| Hydrochloric Acid SCHEMBL29205455 | 0.71 | APEX1 (0.76) | APEX1KMT2AKDM4ELMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL30881912 | 0.71 | APEX1 (0.76) | APEX1KMT2AKDM4ELMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009038685-A1 | LIGANDS FOR COPPER-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-03-26 | — | — | WO | disclosed |