Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | NOS1 | P29475 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2980594 | 0.88 | MAPT (0.51) | MAPTCYP3A4NOS1LMNAALOX15 | |
| SCHEMBL649172 | 0.70 | CYP3A4 (0.49) | MAPTCYP3A4NOS1LMNAALOX15 | |
| SCHEMBL3887990 | 0.67 | CYP3A4 (0.57) | MAPTCYP3A4NOS1LMNAALOX15 | |
| SCHEMBL29394925 | 0.67 | MAPT (1.00) | MAPTCYP3A4NOS1LMNAALOX15 | |
| SCHEMBL271522 | 0.67 | MAPT (1.00) | MAPTCYP3A4NOS1LMNAALOX15 | |
| SCHEMBL29993384 | 0.66 | PARP1 (0.73) | MAPTCYP3A4NOS1LMNAALOX15 | |
| SCHEMBL6008297 | 0.66 | PARP1 (0.73) | MAPTCYP3A4NOS1LMNAALOX15 | |
| SCHEMBL11819338 | 0.66 | CYP3A4 (0.56) | MAPTCYP3A4NOS1LMNAALOX15 | |
| SCHEMBL921416 | 0.66 | DAO (0.51) | MAPTCYP3A4NOS1LMNAALOX15 | |
| SCHEMBL30833662 | 0.66 | DAO (0.51) | MAPTCYP3A4NOS1LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484550-B | Sphaelactone derivative and preparation method and application thereof | 中国人民解放军第四军医大学 | 2020-04-07 | — | — | CN | disclosed |
| US-8361627-B2 | Anti-corrosion layer for aluminum and magnesium alloys | EADS DEUTSCHLAND GMBH (DE) | 2013-01-29 | — | — | US | disclosed |
| US-20120021232-A1 | ANTI-CORROSION LAYER FOR ALUMINUM AND MAGNESIUM ALLOYS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-01-26 | — | — | US | disclosed |
| EP-2379623-A1 | ANTI-CORROSION LAYER FOR ALUMINUM AND MAGNESIUM ALLOYS | EADS Deutschland GmbH (DE) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010081757-A1 | ANTI-CORROSION LAYER FOR ALUMINUM AND MAGNESIUM ALLOYS | EADS DEUTSCHLAND GMBH (DE) | 2010-07-22 | — | — | WO | disclosed |