Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 7/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060993 | 1.00 | CCR1 (0.36) | CCR1KMT2ACYP2C19SMN1; SMN2TSHR | |
| SCHEMBL4070982 | 0.83 | TSHR (0.40) | CCR1KMT2ACYP2C19SMN1; SMN2TSHR | |
| SCHEMBL2675753 | 0.82 | CCR1 (0.45) | CCR1KMT2A | |
| SCHEMBL4061501 | 0.77 | CCR1 (0.39) | CCR1SMN1; SMN2TSHR | |
| SCHEMBL4061953 | 0.77 | CCR1 (0.32) | CCR1KMT2A | |
| SCHEMBL4069721 | 0.76 | CCR1 (0.37) | CCR1KMT2A | |
| SCHEMBL4068201 | 0.74 | CCR1 (0.32) | CCR1 | |
| SCHEMBL4060673 | 0.72 | CCR1 (0.45) | CCR1KMT2A | |
| SCHEMBL4065347 | 0.72 | ANPEP (0.32) | KMT2ATSHR | |
| SCHEMBL4065263 | 0.71 | CCR1 (0.46) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966443-B1 | HETEROARYL-HEXANOIC ACID AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS SELECTIVE INHIBITORS OF MIP-1-ALPHA BINDING TO ITS CCR1 RECEPTOR | PFIZER (US) | 2009-01-28 | — | — | EP | disclosed |