⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21591048 | 1.00 | — | — | |
| SCHEMBL236633 | 1.00 | — | — | |
| SCHEMBL803674 | 0.93 | CYP1A2 (0.62) | — | |
| SCHEMBL7891041 | 0.93 | CYP1A2 (0.62) | — | |
| SCHEMBL10359413 | 0.93 | CYP1A2 (0.62) | — | |
| SCHEMBL24837421 | 0.91 | CYP1A2 (0.66) | — | |
| Bromide SCHEMBL27620628 | 0.91 | CYP1A2 (0.60) | — | |
| SCHEMBL2980496 | 0.87 | CYP1A2 (0.50) | — | |
| SCHEMBL4088645 | 0.87 | — | — | |
| SCHEMBL4087890 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184561-A | Synthetic method and application of R-N-methyl-2- (2-hydroxyethyl) pyrrolidine | 济宁晟泰药业有限公司 | 2024-06-14 | — | — | CN | claimed |
| EP-1478645-A2 | QUINOLINONE DERIVATIVES FOR TREATING CELL PROLIFERATION RELATED DISORDERS | Amgen Inc. (US) | 2004-11-24 | — | — | EP | claimed |
| WO-2003066630-A2 | QUINOLINONE DERIVATIVES FOR TREATING CELL PROLIFERATION RELATED DISORDERS | AMGEN INC. (US) | 2003-08-14 | — | — | WO | claimed |
| CN-121850925-A | Industrial preparation method and application of clemastine fumarate | 广东先强药业有限公司 | 2026-04-14 | — | — | CN | disclosed |
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| US-20240366615-A1 | POLQ INHIBITORS | ASTRAZENECA UK LIMITED (GB) | 2024-11-07 | — | — | US | disclosed |
| CN-118851971-A | Efficient synthesis method of clemastine fumarate | 南京斯泰尔医药科技有限公司 | 2024-10-29 | — | — | CN | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |
| CN-118184561-A | Synthetic method and application of R-N-methyl-2- (2-hydroxyethyl) pyrrolidine | 济宁晟泰药业有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-118184561-A | Synthetic method and application of R-N-methyl-2- (2-hydroxyethyl) pyrrolidine | 济宁晟泰药业有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-118184561-A | Synthetic method and application of R-N-methyl-2- (2-hydroxyethyl) pyrrolidine | 济宁晟泰药业有限公司 | 2024-06-14 | — | — | CN | disclosed |
| EP-1513814-B1 | NOVEL PIPERIDINE COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2010-03-17 | — | — | EP | disclosed |
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |
| US-20090203763-A1 | SUBSTITUTED BENZHYDRYLETHERS | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | US | disclosed |
| US-20090203763-A1 | SUBSTITUTED BENZHYDRYLETHERS | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | US | disclosed |
| US-20090203763-A1 | SUBSTITUTED BENZHYDRYLETHERS | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | US | disclosed |
| WO-2009094457-A2 | SUBSTITUTED BENZHYDRYLETHERS | AUSPEX PHARMACEUTICALS (US) | 2009-07-30 | — | — | WO | disclosed |
| WO-2009094457-A2 | SUBSTITUTED BENZHYDRYLETHERS | AUSPEX PHARMACEUTICALS (US) | 2009-07-30 | — | — | WO | disclosed |
| EP-2079703-A1 | INDAZOLE DERIVATIVES USEFUL AS L-CPT1 INHIBITORS | F. Hoffmann-Roche AG (CH) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008052898-A1 | INDAZOLE DERIVATIVES USEFUL AS L-CPT1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-05-08 | — | — | WO | disclosed |