SCHEMBL4065702

SCHEMBL4065702

CC1C(=O)N(Cc2ccc3c(N)ncnc3c2)CCN1Cc1cc(-c2ccc(Cl)s2)no1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 19/20 0.46
DGAT1 O75907 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL1384992 0.94 F10 (0.41) F10DGAT1
SCHEMBL4066600 0.88 F10 (0.45) F10
SCHEMBL4066599 0.88 F10 (0.45) F10
SCHEMBL4390612 0.88 F10 (0.47) F10DGAT1
SCHEMBL4070203 0.85 F10 (0.61) F10
Trifluoroacetic Acid SCHEMBL1385731 0.84 F10 (0.39) F10DGAT1
Trifluoroacetic Acid SCHEMBL1384851 0.83 F10 (0.40) F10
SCHEMBL4391946 0.81 F10 (0.46) F10DGAT1
SCHEMBL4391950 0.81 F10 (0.46) F10DGAT1
SCHEMBL1652586 0.80 F10 (0.47) F10DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1208097-B1 SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS AVENTIS PHARMA INC (US) 2009-02-18 EP claimed