Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 20/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 14/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3595733 | 0.91 | SLC6A2 (0.60) | SLC6A2SLC6A3KCNH2SLC6A4 | |
| SCHEMBL3615773 | 0.89 | SLC6A2 (0.47) | SLC6A2SLC6A3KCNH2SLC6A4 | |
| SCHEMBL3615768 | 0.89 | SLC6A2 (0.47) | SLC6A2SLC6A3KCNH2SLC6A4 | |
| SCHEMBL4065844 | 0.88 | SLC6A2 (0.77) | SLC6A2SLC6A3KCNH2SLC6A4 | |
| SCHEMBL4058041 | 0.86 | SLC6A2 (0.78) | SLC6A2SLC6A3KCNH2SLC6A4 | |
| SCHEMBL4946356 | 0.86 | SLC6A2 (0.78) | SLC6A2SLC6A3KCNH2SLC6A4 | |
| SCHEMBL3600695 | 0.86 | SLC6A2 (0.78) | SLC6A2SLC6A3KCNH2SLC6A4 | |
| SCHEMBL3611606 | 0.84 | SLC6A2 (0.61) | SLC6A2SLC6A3KCNH2SLC6A4 | |
| SCHEMBL3595435 | 0.84 | SLC6A2 (0.77) | SLC6A2SLC6A3KCNH2SLC6A4 | |
| SCHEMBL3606081 | 0.84 | SLC6A2 (0.77) | SLC6A2SLC6A3KCNH2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061776-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | Wyeth a Corporation of the State of Delaware (US) | 2009-05-27 | — | — | EP | claimed |
| WO-2008073459-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-06-19 | — | — | WO | claimed |
| EP-2061776-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | Wyeth a Corporation of the State of Delaware (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008073459-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |