Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.55 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.55 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23340463 | 0.94 | CACNA2D1 (0.50) | CYP1A2TDP1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL18713017 | 0.93 | CYP1A2 (0.55) | CYP1A2TDP1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL27260584 | 0.89 | CACNA2D1 (0.53) | CYP1A2TDP1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL4550243 | 0.89 | PIK3CD (0.52) | CYP1A2TDP1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL23173214 | 0.88 | CACNA2D1 (0.53) | CYP1A2TDP1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL27895314 | 0.87 | CACNA2D1 (0.56) | CYP1A2TDP1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL27571743 | 0.86 | CACNA2D1 (0.58) | CYP1A2TDP1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL13993923 | 0.85 | SMN1; SMN2 (0.49) | CYP1A2TDP1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL23173333 | 0.84 | PIK3CD (0.44) | CYP1A2TDP1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL25513778 | 0.84 | PIK3CD (0.44) | CYP1A2TDP1CACNA2D1CACNA1BCACNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066659-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2009-06-10 | — | — | EP | claimed |
| WO-2008040492-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2008-04-10 | — | — | WO | claimed |
| WO-2024073626-A2 | ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS | NUVATION BIO INC. (US) | 2024-04-04 | — | — | WO | disclosed |
| EP-2066659-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008040492-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2008-04-10 | — | — | WO | disclosed |