Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16656686 | 1.00 | TSHR (0.58) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL19242339 | 1.00 | TSHR (0.58) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL10081322 | 1.00 | TSHR (0.58) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL495106 | 0.96 | TSHR (0.54) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL495396 | 0.96 | TSHR (0.54) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL496032 | 0.96 | TSHR (0.54) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL495766 | 0.96 | TSHR (0.54) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL494612 | 0.96 | TSHR (0.54) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL494434 | 0.96 | TSHR (0.54) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL495060 | 0.96 | TSHR (0.54) | TSHRL3MBTL1LMNAALDH1A1PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1166766-B1 | EXTERNAL PREPARATION COMPOSITIONS | KAO CORP (JP) | 2009-10-21 | — | — | EP | disclosed |
| US-7351716-B2 | Dermatological preparations | KAO CORPORATION (JP) | 2008-04-01 | — | — | US | disclosed |
| US-20040115162-A1 | Dermatological preparations | KAO CORPORATION (JP) | 2004-06-17 | — | — | US | disclosed |
| US-6685953-B1 | WATER RETENTION CAPACITY; MOISTURIZER; ALKOXYALKYAMIDES OF ALKYLENEDICARBOXYLIC ACIDS | KAO CORPORATION (JP) | 2004-02-03 | — | — | US | disclosed |
| EP-1166766-A1 | EXTERNAL PREPARATION COMPOSITIONS | Kao Corporation (JP) | 2002-01-02 | — | — | EP | disclosed |