Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.62 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30477201 | 0.88 | GRIA1 (0.73) | GRIA1GRIA3PDE4DADORA2AADORA1 | |
| SCHEMBL1884996 | 0.84 | GRIA1 (0.79) | GRIA1GRIA3PDE4DGABRA1GABRG2 | |
| SCHEMBL4072454 | 0.81 | GRIA1 (0.66) | GRIA1GRIA3PDE4DADORA2AADORA1 | |
| SCHEMBL1880152 | 0.80 | GRIA1 (0.70) | GRIA1GRIA3PDE4DLMNAHPGD | |
| SCHEMBL14889214 | 0.80 | GRIA1 (0.73) | GRIA1GRIA3PDE4DADORA2AADORA1 | |
| SCHEMBL1882807 | 0.79 | GRIA1 (0.69) | GRIA1GRIA3PDE4DMEN1KMT2A | |
| SCHEMBL1883400 | 0.79 | GRIA1 (0.69) | GRIA1GRIA3PDE4DADORA2AADORA1 | |
| SCHEMBL1884155 | 0.79 | GRIA1 (0.69) | GRIA1GRIA3PDE4DMEN1LMNA | |
| SCHEMBL1879825 | 0.79 | GRIA1 (0.68) | GRIA1GRIA3PDE4DGABRA1GABRG2 | |
| SCHEMBL1881660 | 0.78 | GRIA1 (0.70) | GRIA1GRIA3PDE4DGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300396-B1 | 1,2-DIHYDROPYRIDINE COMPOUNDS, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF | EISAI R&D MAN CO LTD (JP) | 2009-01-14 | — | — | EP | disclosed |