Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.88 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3528166 | 0.94 | — | — | |
| Iodide SCHEMBL3260442 | 0.85 | HDAC8 (0.75) | HDAC8KCNH2SLC22A2SLC22A1SLC22A3 | |
| SCHEMBL8988114 | 0.71 | HDAC8 (1.00) | HDAC8KCNH2ACHETSHRHRH1 | |
| SCHEMBL862249 | 0.71 | — | — | |
| SCHEMBL4072516 | 0.71 | KCNH2 (0.64) | HDAC8KCNH2KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5833068 | 0.70 | HDAC8 (0.95) | HDAC8KCNH2ACHETSHRHRH1 | |
| Iodide SCHEMBL30133746 | 0.70 | HDAC8 (0.95) | HDAC8ACHETSHRHRH1PDE4D | |
| SCHEMBL28990980 | 0.67 | — | — | |
| SCHEMBL8241353 | 0.62 | — | — | |
| SCHEMBL3719754 | 0.61 | HDAC8 (0.55) | HDAC8SLC22A2SLC22A1SLC22A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997475-A2 | Composition comprising at least one substituted derivative of acetylenic carbocyanine, method of treating keratinous fibres implementing it and device | L'Oréal (FR) | 2008-12-03 | — | — | EP | claimed |
| EP-2018848-B1 | Hair composition comprising at least one fluorescent dye and at least one alkali hydroxide agent and method of simultaneous styling, dyeing and/or lightening. | OREAL (FR) | 2013-01-09 | — | — | EP | disclosed |
| EP-2018848-A2 | Hair composition comprising at least one fluorescent dye and at least one alkali hydroxide agent and method of simultaneous styling, dyeing and/or lightening. | L'Oreal (FR) | 2009-01-28 | — | — | EP | disclosed |
| EP-1997475-A2 | Composition comprising at least one substituted derivative of acetylenic carbocyanine, method of treating keratinous fibres implementing it and device | L'Oréal (FR) | 2008-12-03 | — | — | EP | disclosed |