SCHEMBL4068647

SCHEMBL4068647

CCCC[C@H](N)C(=O)OC(=O)[C@@H](N)CCSC

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 3/20 0.41
SLC15A1 P46059 1/20 0.41
SLC1A2 P43004 2/20 0.39
SLC1A1 P43005 2/20 0.39
SLC1A3 P43003 1/20 0.39
METAP1 P53582 2/20 0.38
METAP2 P50579 1/20 0.38
DPP4 P27487 2/20 0.38
DPP8 Q6V1X1 2/20 0.38
DPP9 Q86TI2 2/20 0.38
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
NOD1 Q9Y239 1/20 0.36
MARS1 P56192 4/20 0.35
RNPEP Q9H4A4 1/20 0.35
GRIK1 P39086 1/20 0.34
GRIK2 Q13002 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL162031 0.89 RNPEP (0.42) METAP1METAP2MARS1RNPEP
SCHEMBL5617582 0.89 RNPEP (0.42) METAP1METAP2MARS1RNPEP
SCHEMBL20996747 0.89 RNPEP (0.42) METAP1METAP2MARS1RNPEP
SCHEMBL6045793 0.89 RNPEP (0.42) METAP1METAP2MARS1RNPEP
SCHEMBL21114423 0.87 DPP7 (0.50) DPP7SLC15A1SLC1A2SLC1A1SLC1A3
SCHEMBL5497695 0.87 DPP7 (0.50) DPP7SLC15A1SLC1A2SLC1A1SLC1A3
SCHEMBL6445484 0.87 DPP7 (0.50) DPP7SLC15A1SLC1A2SLC1A1SLC1A3
SCHEMBL5586890 0.86 GSR (0.40) DPP7METAP1METAP2DPP4DPP8
SCHEMBL1345094 0.85 GSR (0.47) DPP7METAP1METAP2DPP4DPP8
SCHEMBL6574895 0.83 GSR (0.46) DPP7METAP1METAP2DPP4DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0226304-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1991-08-28 EP claimed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP claimed
EP-2032701-A1 POLYNUCLEOTIDES AND POLYPEPTIDE SEQUENCES INVOLVED IN CANCER Alethia Biotherapeutics Inc. (CA) 2009-03-11 EP disclosed
WO-2007147265-A1 POLYNUCLEOTIDES AND POLYPEPTIDE SEQUENCES INVOLVED IN CANCER ALETHIA BIOTHERAPEUTICS INC. (CA) 2007-12-27 WO disclosed
EP-1356279-A2 WATER-SOLUBLE, FLUORESCENT, & ELECTROPHORETICALLY MOBILE PEPTIDIC SUBSTRATES FOR ENZYMATIC REACTIONS AND METHODS FOR THEIR USE IN HIGH-THROUGHPUT SCREENING ASSAYS NANOGEN (US) 2003-10-29 EP disclosed
WO-2002061114-A9 WATER-SOLUBLE, FLUORESCENT AND MOBILE PEPTIDE SUBSTRATES NANOGEN INC (US) 2003-08-07 WO disclosed
WO-2002061114-A2 WATER-SOLUBLE, FLUORESCENT AND MOBILE PEPTIDE SUBSTRATES NANOGEN, INC. (US) 2002-08-08 WO disclosed
EP-0288087-B1 Method for producing protein containing nonprotein amino acids WAKUNAGA SEIYAKU KK (JP) 1995-02-22 EP disclosed
US-4879223-A Method for producing protein containing nonprotein amino acids WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1989-11-07 US disclosed
EP-0288087-A2 Method for producing protein containing nonprotein amino acids WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1988-10-26 EP disclosed