Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 15/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 14/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 11/20 | 0.46 |
| ▸ | LMNA | P02545 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | USP2 | O75604 | 12/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 10/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RAF1 | P04049 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3939158 | 0.88 | FLT1 (0.48) | LMNAALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL3929417 | 0.88 | STK17B (0.51) | CYP1A2CYP3A4CLK4ALDH1A1USP2 | |
| SCHEMBL4076235 | 0.87 | MAP3K8 (0.43) | CLK4ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL3928997 | 0.86 | CYP1A2 (0.42) | CYP1A2CYP3A4CLK4LMNAALDH1A1 | |
| SCHEMBL3931001 | 0.84 | IKBKB (0.42) | LMNAALDH1A1KDM4EFLT1EGFR | |
| SCHEMBL4068884 | 0.84 | TYK2 (0.53) | CYP1A2CYP3A4CLK4ALDH1A1TSHR | |
| SCHEMBL4007903 | 0.82 | STK17B (0.42) | CYP1A2CYP3A4CLK4LMNAALDH1A1 | |
| SCHEMBL4008652 | 0.81 | CDK1 (0.41) | CYP1A2CYP3A4CLK4ALDH1A1USP2 | |
| SCHEMBL4076692 | 0.80 | CYP1A2 (0.55) | CYP1A2CYP3A4CLK4LMNAALDH1A1 | |
| SCHEMBL13960063 | 0.80 | NPC1 (0.44) | CYP1A2CYP3A4CLK4ALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042913-A1 | Indolylalkylthienopyrimidylamines as modulators of the EP2 receptor | BAYER SCHERING PHARMA AG (DE) | 2009-02-12 | — | — | US | claimed |
| EP-2014662-A1 | Indolyl alkyl thieno-pyrimidyl amines as modulators of EP2 receptors | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-01-14 | — | — | EP | claimed |
| US-20090042913-A1 | Indolylalkylthienopyrimidylamines as modulators of the EP2 receptor | BAYER SCHERING PHARMA AG (DE) | 2009-02-12 | — | — | US | disclosed |
| US-20090042913-A1 | Indolylalkylthienopyrimidylamines as modulators of the EP2 receptor | BAYER SCHERING PHARMA AG (DE) | 2009-02-12 | — | — | US | disclosed |
| EP-2014662-A1 | Indolyl alkyl thieno-pyrimidyl amines as modulators of EP2 receptors | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042913-A1 | Indolylalkylthienopyrimidylamines as modulators of the EP2 receptor | PTGER2, PTGER1, PTGDR2 | CYP1A2 403/4885CYP3A4 1400/4885CLK4 4381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.