Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.47 |
| ▸ | CNR1 | P21554 | 8/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464719 | 0.83 | CNR2 (0.56) | CNR2CNR1ALDH1A1TSHR | |
| SCHEMBL469403 | 0.81 | CNR2 (0.69) | CNR2CNR1GAANPC1RAB9A | |
| SCHEMBL1464391 | 0.80 | CNR2 (0.55) | CNR2CNR1GAAABCC9ABCC8 | |
| SCHEMBL1464594 | 0.77 | CNR2 (0.57) | CNR2CNR1GAAABCC9ABCC8 | |
| SCHEMBL1463790 | 0.75 | CNR2 (0.54) | CNR2CNR1GAAABCC9ABCC8 | |
| SCHEMBL1464878 | 0.75 | CNR2 (0.64) | CNR2CNR1GAAABCC9ABCC8 | |
| SCHEMBL1464948 | 0.74 | CNR2 (0.56) | CNR2CNR1ABCC9ABCC8KCNJ11 | |
| SCHEMBL1466231 | 0.72 | CNR2 (0.53) | CNR2CNR1GAAL3MBTL1ABCC9 | |
| SCHEMBL1464362 | 0.72 | CNR2 (0.57) | CNR2CNR1GAAABCC9ABCC8 | |
| SCHEMBL1464005 | 0.72 | CNR2 (0.57) | CNR2CNR1GAAABCC9ABCC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |