Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3993426 | 0.95 | MAPK14 (0.54) | MAPK14 | |
| SCHEMBL4062018 | 0.95 | MAPK14 (0.51) | MAPK14 | |
| SCHEMBL4061872 | 0.92 | MAPK14 (0.58) | MAPK14 | |
| SCHEMBL4071412 | 0.90 | MAPK14 (0.57) | MAPK14 | |
| SCHEMBL3992706 | 0.84 | MAPK14 (0.60) | MAPK14 | |
| SCHEMBL4058381 | 0.84 | MAPK14 (0.45) | MAPK14 | |
| SCHEMBL4065568 | 0.84 | MAPK14 (0.45) | MAPK14 | |
| SCHEMBL4069774 | 0.82 | MAPK14 (0.45) | MAPK14 | |
| SCHEMBL4060518 | 0.80 | BRAF (0.38) | MAPK14 | |
| SCHEMBL3992935 | 0.78 | MAPK14 (0.54) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4159212-A1 | P38 KINASE INHIBITORS REDUCE DUX4 AND DOWNSTREAM GENE EXPRESSION FOR THE TREATMENT OF FSHD | Fulcrum Therapeutics, Inc. (US) | 2023-04-05 | — | — | EP | disclosed |
| EP-1713805-B1 | KINASE INHIBITORS | LILLY CO ELI (US) | 2009-06-10 | — | — | EP | disclosed |