Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.38 |
| ▸ | FRK | P42685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4074439 | 0.90 | MAPK14 (0.46) | MAPK14MAPK11 | |
| SCHEMBL2719973 | 0.89 | MAPK14 (0.44) | MAPK14CYP2C9HSPB1MAPK11EPHA3 | |
| SCHEMBL10226946 | 0.88 | MAPK14 (0.42) | MAPK14CYP2C9HSPB1MAPK11EPHA3 | |
| Trifluoroacetic Acid SCHEMBL2722016 | 0.87 | MAPK14 (0.41) | MAPK14CYP2C9HSPB1MAPK11EPHA3 | |
| SCHEMBL2731413 | 0.84 | MAPK14 (0.43) | MAPK14CYP2C9HSPB1MAPK11 | |
| SCHEMBL10227414 | 0.84 | MAPK14 (0.39) | MAPK14CYP2C9HSPB1MAPK11EPHA3 | |
| SCHEMBL2719290 | 0.84 | MAPK14 (0.44) | MAPK14CYP2C9HSPB1MAPK11EPHA3 | |
| SCHEMBL2718570 | 0.84 | MCHR1 (0.42) | MAPK14CYP2C9HSPB1MAPK11 | |
| SCHEMBL2720144 | 0.83 | MAPK14 (0.44) | MAPK14CYP2C9HSPB1MAPK11EPHA3 | |
| SCHEMBL2722018 | 0.83 | MAPK14 (0.38) | MAPK14CYP2C9HSPB1MAPK11EPHA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2034838-A2 | NOVEL COMPOUNDS | Glaxo Group Limited (GB) | 2009-03-18 | — | — | EP | claimed |
| WO-2007147103-A2 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2007-12-21 | — | — | WO | claimed |