⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22342295 | 0.89 | TSHR (0.35) | — | |
| SCHEMBL261753 | 0.85 | — | — | |
| SCHEMBL145305 | 0.81 | — | — | |
| SCHEMBL149391 | 0.81 | — | — | |
| SCHEMBL2348023 | 0.81 | — | — | |
| SCHEMBL2342604 | 0.75 | AHR (0.33) | — | |
| SCHEMBL19953076 | 0.73 | AHR (0.50) | — | |
| SCHEMBL15352881 | 0.72 | CYP1A2 (0.32) | — | |
| SCHEMBL9060576 | 0.72 | — | — | |
| SCHEMBL57470 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 446 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11712438-B2 | Phenyl derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-08-01 | — | — | US | claimed |
| EP-3625222-B1 | PHENYL DERIVATIVES AS PGE2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-07-21 | — | — | EP | claimed |
| US-20210147435-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | DENALI THERAPEUTICS INC. | 2021-05-20 | — | — | US | claimed |
| EP-3665156-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | Denali Therapeutics Inc. (US) | 2020-06-17 | — | — | EP | claimed |
| US-20200179383-A1 | PHENYL DERIVATIVES AS PGE2 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2020-06-11 | — | — | US | claimed |
| CN-111094233-A | Compounds, compositions and methods | 戴纳立制药公司 | 2020-05-01 | — | — | CN | claimed |
| EP-3625222-A1 | PHENYL DERIVATIVES AS PGE2 RECEPTOR MODULATORS | Idorsia Pharmaceuticals Ltd (CH) | 2020-03-25 | — | — | EP | claimed |
| CN-110612296-A | Phenyl derivatives as PGE2 receptor modulators | 爱杜西亚药品有限公司 | 2019-12-24 | — | — | CN | claimed |
| CN-110382493-A | THIADIAZOLE DERIVATIVES AS PESTICIDES | 拜耳农作物科学股份公司 | 2019-10-25 | — | — | CN | claimed |
| CN-110300522-A | For preventing and treating the composition that harmful microbe includes 1- (Phenoxy-pyridin base) -2- (1,2,4- triazol-1-yl)-alcohol derivative | 拜耳公司 | 2019-10-01 | — | — | CN | claimed |
| CN-1387527-A | Quinazoline derivatives as VEGF inhibitors | ASTRAZENECA AB (SE) | 2002-12-25 | — | — | CN | claimed |
| EP-1244647-A1 | QUINAZOLINE DERIVATIVES AS VEGF INHIBITORS | AstraZeneca AB (SE) | 2002-10-02 | — | — | EP | claimed |
| US-6448264-B2 | ANTIPROLIFERATIVE, -CARCINOGENIC AGENTS, ANTIINFLAMMATORY AND -ARTHRITIS AGENTS; NEURODEGENERATIVE DISEASES, E.G., ALZHEIMER'S DISEASE; CARDIOVASCULAR DISORDERS; VIRICIDES; FUNGICIDES | BRISTOL-MYERS SQUIBB COMPANY | 2002-09-10 | — | — | US | claimed |
| US-20020002178-A1 | Use of 5-thio-, sulfinyl- and sulfonylpyrazolo[3,4-b]- pyridines as cyclin dependent kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2002-01-03 | — | — | US | claimed |
| WO-2001081348-A1 | USE OF 5-THIO-, SULFINYL- AND SULFONYLPYRAZOLO[3,4-b]-PYRIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-11-01 | — | — | WO | claimed |
| WO-2001032651-A1 | QUINAZOLINE DERIVATIVES AS VEGF INHIBITORS | ASTRAZENECA AB (SE) | 2001-05-10 | — | — | WO | claimed |
| EP-1043998-A1 | USE OF PYRAZOLO 3,4-b] PYRIDINE AS CYCLIN DEPENDENT KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-10-18 | — | — | EP | claimed |
| US-6107305-A | Use of pyrazolo [3,4-b] pyridine as cyclin dependent kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-08-22 | — | — | US | claimed |
| WO-1999030710-A1 | USE OF PYRAZOLO [3,4-b] PYRIDINE AS CYCLIN DEPENDENT KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-06-24 | — | — | WO | claimed |
| WO-1997010220-A1 | URACIL DERIVATIVE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-20 | — | — | WO | claimed |