⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4067867 | 0.87 | — | — | |
| SCHEMBL4075589 | 0.64 | KDM4E (0.34) | — | |
| SCHEMBL4438253 | 0.64 | — | — | |
| Potassium SCHEMBL31514255 | 0.64 | PDCD1 (0.33) | — | |
| SCHEMBL5232400 | 0.61 | — | — | |
| SCHEMBL5675428 | 0.58 | — | — | |
| SCHEMBL2784363 | 0.58 | — | — | |
| SCHEMBL4339846 | 0.58 | — | — | |
| SCHEMBL4073821 | 0.57 | — | — | |
| SCHEMBL22102661 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325992-A1 | COMPOUND HAVING CYCLIC GROUP BOUND THERETO THROUGH SPIRO BINDING AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-12-31 | — | — | US | disclosed |
| EP-2055705-A1 | COMPOUND HAVING CYCLIC GROUP BOUND THERETO THROUGH SPIRO BINDING AND USE THEREOF | Ono Pharmaceutical CO., LTD. (JP) | 2009-05-06 | — | — | EP | disclosed |