⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4066242 | 0.78 | — | — | |
| SCHEMBL712267 | 0.67 | — | — | |
| SCHEMBL238844 | 0.65 | — | — | |
| SCHEMBL173406 | 0.64 | PDPK1 (0.45) | — | |
| SCHEMBL12604725 | 0.64 | PDPK1 (0.45) | — | |
| SCHEMBL23335459 | 0.64 | PDPK1 (0.45) | — | |
| SCHEMBL667621 | 0.64 | — | — | |
| Ammonia Solution, Strong SCHEMBL29261101 | 0.64 | PDPK1 (0.45) | — | |
| SCHEMBL3313192 | 0.64 | PDPK1 (0.45) | — | |
| SCHEMBL3310781 | 0.64 | PDPK1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325992-A1 | COMPOUND HAVING CYCLIC GROUP BOUND THERETO THROUGH SPIRO BINDING AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-12-31 | — | — | US | disclosed |
| EP-2055705-A1 | COMPOUND HAVING CYCLIC GROUP BOUND THERETO THROUGH SPIRO BINDING AND USE THEREOF | Ono Pharmaceutical CO., LTD. (JP) | 2009-05-06 | — | — | EP | disclosed |