Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 5/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | USP19 | O94966 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1002842 | 0.87 | AVPR1A (0.46) | AVPR1AMCHR1GPR119ESR2PKM | |
| SCHEMBL4069303 | 0.81 | AVPR1A (0.46) | AVPR1AMCHR1GPR119ESR2USP2 | |
| SCHEMBL12701623 | 0.79 | AVPR1A (0.50) | AVPR1AMCHR1GPR119ESR2USP2 | |
| SCHEMBL30623466 | 0.79 | AVPR1A (0.50) | AVPR1AMCHR1GPR119ESR2USP2 | |
| SCHEMBL4067687 | 0.78 | AVPR1A (0.46) | AVPR1AMCHR1NAMPTGPR119ESR2 | |
| SCHEMBL17586450 | 0.78 | AVPR1A (0.49) | AVPR1AMCHR1GPR119ESR2USP2 | |
| SCHEMBL4316200 | 0.77 | AVPR1A (0.43) | AVPR1AMCHR1NAMPTGPR119 | |
| SCHEMBL4074124 | 0.76 | AVPR1A (0.46) | AVPR1AMCHR1NAMPTGPR119ESR2 | |
| SCHEMBL18643673 | 0.75 | MCHR1 (0.45) | AVPR1AMCHR1GPR119PKM | |
| SCHEMBL30743086 | 0.75 | NR1H2 (0.56) | AVPR1ANAMPTGPR119ESR2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072519-A1 | DIARYL KETIMINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-06-24 | — | — | EP | disclosed |