⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7596977 | 0.81 | — | — | |
| SCHEMBL14542359 | 0.77 | — | — | |
| SCHEMBL3116028 | 0.75 | — | — | |
| SCHEMBL4012084 | 0.70 | — | — | |
| SCHEMBL6846074 | 0.70 | — | — | |
| SCHEMBL7482380 | 0.70 | — | — | |
| SCHEMBL8513535 | 0.67 | — | — | |
| SCHEMBL5054800 | 0.67 | TAAR1 (0.33) | — | |
| SCHEMBL13149370 | 0.67 | — | — | |
| SCHEMBL1053132 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608637-B2 | Pharmaceutical composition for treatment of diseases associated with decrease in bone mass comprising EP4 agonist as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-10-27 | — | — | US | disclosed |
| US-20050020686-A1 | Remedies for diseases with bone mass loss having ep4 agonist as the active ingredient | ONO PHARMACEUTICAL CO. LTD. (JP) | 2005-01-27 | — | — | US | disclosed |