⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2796481 | 0.84 | — | — | |
| SCHEMBL1723555 | 0.72 | — | — | |
| SCHEMBL8729582 | 0.72 | — | — | |
| SCHEMBL113678 | 0.69 | — | — | |
| SCHEMBL8728944 | 0.67 | — | — | |
| SCHEMBL4096257 | 0.67 | — | — | |
| SCHEMBL385743 | 0.64 | — | — | |
| SCHEMBL9864322 | 0.62 | — | — | |
| SCHEMBL3521050 | 0.61 | — | — | |
| SCHEMBL2054 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4396775-A | Homoserine aldehyde derivatives for mugineic acids synthesis | SUNTORY LIMITED (JP) | 1983-08-02 | — | — | US | claimed |
| US-10457700-B2 | Platinum prodrugs and methods of making and using thereof | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2019-10-29 | — | — | US | disclosed |
| US-20180044362-A1 | PLATINUM PRODRUGS AND METHODS OF MAKING AND USING THEREOF | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2018-02-15 | — | — | US | disclosed |
| EP-2010539-B1 | STEREOSELECTIVE REDUCTION OF A MORPHINONE | NEKTAR THERAPEUTICS (US) | 2017-06-14 | — | — | EP | disclosed |
| WO-2016144889-A1 | PLATINUM PRODRUGS AND METHODS OF MAKING AND USING THEREOF | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2016-09-15 | — | — | WO | disclosed |
| US-8563726-B2 | Stereoselective reduction of a morphinone | NEKTAR THERAPEUTICS (US) | 2013-10-22 | — | — | US | disclosed |
| US-20130018190-A1 | STEREOSELECTIVE REDUCTION OF A MORPHINONE | NEKTAR THERAPEUTICS (US) | 2013-01-17 | — | — | US | disclosed |
| US-8183376-B2 | Stereoselective reduction of a morphinone | NEKTAR THERAPEUTICS (US) | 2012-05-22 | — | — | US | disclosed |
| US-20090221766-A1 | STEREOSELECTIVE REDUCTION OF A MORPHINONE | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2009-09-03 | — | — | US | disclosed |
| EP-2010539-A2 | STEREOSELECTIVE REDUCTION OF A MORPHINONE | Nektar Therapeutics AL, Corporation (US) | 2009-01-07 | — | — | EP | disclosed |
| EP-0983257-A1 | AROMATIC SULFONYL ALPHA-CYCLOAMINO HYDROXAMIC ACID COMPOUNDS | Monsanto Company (US) | 2000-03-08 | — | — | EP | disclosed |
| EP-0939629-A1 | THIOL SULFONAMIDE METALLOPROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1999-09-08 | — | — | EP | disclosed |
| WO-1999025687-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 1999-05-27 | — | — | WO | disclosed |
| EP-0609058-B1 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO CO (JP) | 1998-12-09 | — | — | EP | disclosed |
| WO-1998039315-A1 | AROMATIC SULFONYL ALPHA-CYCLOAMINO HYDROXAMIC ACID COMPOUNDS | MONSANTO COMPANY (US) | 1998-09-11 | — | — | WO | disclosed |
| WO-1998003166-A1 | THIOL SULFONAMIDE METALLOPROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1998-01-29 | — | — | WO | disclosed |
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |
| EP-0609058-A2 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1994-08-03 | — | — | EP | disclosed |
| US-5134116-A | Mixture of dyes for black dye donor for thermal color proofing | EASTMAN KODAK COMPANY (US) | 1992-07-28 | — | — | US | disclosed |
| US-4396775-A | Homoserine aldehyde derivatives for mugineic acids synthesis | SUNTORY LIMITED (JP) | 1983-08-02 | — | — | US | disclosed |