Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12430270 | 0.71 | HTR2C (0.53) | HTR2C | |
| SCHEMBL1896512 | 0.68 | HTR2C (1.00) | HTR2C | |
| SCHEMBL1891028 | 0.66 | HTR2C (1.00) | HTR2C | |
| SCHEMBL1893905 | 0.66 | HTR2C (1.00) | HTR2C | |
| SCHEMBL12430282 | 0.65 | HTR2C (0.47) | HTR2C | |
| SCHEMBL1897800 | 0.64 | HTR2C (1.00) | HTR2C | |
| SCHEMBL1893040 | 0.64 | HTR2C (1.00) | HTR2C | |
| SCHEMBL1896732 | 0.64 | HTR2C (0.88) | HTR2C | |
| SCHEMBL12430267 | 0.64 | HTR2C (0.53) | HTR2C | |
| SCHEMBL1896649 | 0.64 | HTR2C (0.88) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1796663-A4 | TRICYCLIC HETEROARYL PIPERAZINES, PYRROLIDINES AND AZETIDINES AS SEROTONIN RECEPTOR MODULATORS | ATHERSYS INC (US) | 2009-08-05 | — | — | EP | disclosed |
| EP-1796663-A2 | TRICYCLIC HETEROARYL PIPERAZINES, PYRROLIDINES AND AZETIDINES AS SEROTONIN RECEPTOR MODULATORS | Athersys, Inc. (US) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006028961-A2 | TRICYCLIC HETEROARYL PIPERAZINES, PYRROLIDINES AND AZETIDINES AS SEROTONIN RECEPTOR MODULATORS | ATHERSYS, INC. (US) | 2006-03-16 | — | — | WO | disclosed |