Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL555408 | 1.00 | DPP4 (0.62) | DPP4KMT2ALMNAMAPK1ADORA2A | |
| SCHEMBL4073092 | 1.00 | DPP4 (0.62) | DPP4KMT2ALMNAMAPK1ADORA2A | |
| Hydrochloric Acid SCHEMBL555194 | 0.99 | DPP4 (0.61) | DPP4KMT2ALMNAMAPK1ADORA2A | |
| Hydrochloric Acid SCHEMBL27582646 | 0.99 | DPP4 (0.61) | DPP4KMT2ALMNAMAPK1ADORA2A | |
| Hydrochloric Acid SCHEMBL555193 | 0.99 | DPP4 (0.61) | DPP4KMT2ALMNAMAPK1ADORA2A | |
| SCHEMBL556432 | 0.94 | DPP4 (0.59) | DPP4KMT2ALMNAMAPK1ADORA2A | |
| SCHEMBL556285 | 0.87 | DPP4 (0.61) | DPP4KMT2ALMNAMAPK1ADORA2A | |
| SCHEMBL557054 | 0.87 | DPP4 (0.52) | DPP4KMT2ALMNAMAPK1ADORA2A | |
| SCHEMBL556313 | 0.86 | DPP4 (0.51) | DPP4KMT2ALMNAMAPK1ADORA2A | |
| SCHEMBL556304 | 0.85 | DPP4 (0.50) | DPP4KMT2ALMNAMAPK1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298769-B1 | Xanthin derivatives, their production and utilisation as medicine | BOEHRINGER INGELHEIM PHARMA (DE) | 2013-10-30 | — | — | EP | claimed |
| EP-1757606-B1 | Xanthinderivatives for use as medical agents and the preparation thereof | BOEHRINGER INGELHEIM PHARMA (DE) | 2009-05-06 | — | — | EP | claimed |
| EP-1368349-B1 | XANTHINE DERIVATIVE, PRODUCTION AND USE THEREOF AS A MEDICAMENT | BOEHRINGER INGELHEIM PHARMA (DE) | 2007-02-14 | — | — | EP | claimed |