Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | TLR4 | O00206 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4413178 | 0.79 | SIRT2 (0.55) | SIRT2TLR4TLR2PARP10KAT6A | |
| SCHEMBL27996034 | 0.75 | SIRT2 (0.56) | SIRT2TLR4TLR2CCNA2CDK2 | |
| SCHEMBL2209064 | 0.74 | TLR4 (0.53) | SIRT2TLR4TLR2PARP10MAOA | |
| SCHEMBL2207146 | 0.74 | TLR4 (0.53) | SIRT2TLR4TLR2PARP10MAOA | |
| SCHEMBL2202599 | 0.74 | TLR4 (0.53) | SIRT2TLR4TLR2PARP10MAOA | |
| SCHEMBL29818651 | 0.74 | TLR4 (0.53) | SIRT2TLR4TLR2PARP10MAOA | |
| SCHEMBL29819321 | 0.74 | TLR4 (0.53) | SIRT2TLR4TLR2PARP10MAOA | |
| Ammonia Solution, Strong SCHEMBL2207095 | 0.72 | TLR4 (0.52) | SIRT2TLR4TLR2PARP10MAOA | |
| SCHEMBL2209290 | 0.72 | TLR4 (0.51) | SIRT2TLR4TLR2PARP10 | |
| SCHEMBL29819300 | 0.72 | TLR4 (0.51) | SIRT2TLR4TLR2PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091955-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | Acucela, Inc. (US) | 2009-08-26 | — | — | EP | disclosed |
| WO-2009045479-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. (US) | 2009-04-09 | — | — | WO | disclosed |