Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 4/20 | 0.60 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4068400 | 0.89 | CXCR4 (0.49) | CXCR4KDM1AMAOBRCOR1CYP2D6 | |
| SCHEMBL4070793 | 0.88 | CXCR4 (0.54) | CXCR4CYP2D6CYP3A4ALDH1A1TAAR1 | |
| SCHEMBL4075810 | 0.88 | CXCR4 (0.59) | CXCR4CYP2D6CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL4067735 | 0.87 | CXCR4 (0.52) | CXCR4CYP2D6CYP3A4ALDH1A1TAAR1 | |
| SCHEMBL4069468 | 0.87 | CXCR4 (0.52) | CXCR4CYP2D6CYP3A4ALDH1A1TAAR1 | |
| SCHEMBL2694625 | 0.83 | CXCR4 (0.80) | CXCR4KDM1AMAOBRCOR1CYP2D6 | |
| SCHEMBL4073706 | 0.82 | CXCR4 (0.51) | CXCR4CYP2D6CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL4072232 | 0.81 | CXCR4 (0.52) | CXCR4CYP2D6CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL4233758 | 0.80 | CXCR4 (0.59) | CXCR4KDM1AMAOBRCOR1CYP2D6 | |
| SCHEMBL4073802 | 0.80 | CXCR4 (0.51) | CXCR4CYP2D6CYP3A4ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325992-A1 | COMPOUND HAVING CYCLIC GROUP BOUND THERETO THROUGH SPIRO BINDING AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-12-31 | — | — | US | disclosed |
| EP-2055705-A1 | COMPOUND HAVING CYCLIC GROUP BOUND THERETO THROUGH SPIRO BINDING AND USE THEREOF | Ono Pharmaceutical CO., LTD. (JP) | 2009-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325992-A1 | COMPOUND HAVING CYCLIC GROUP BOUND THERETO THROUGH SPIRO BINDING AND USE THEREOF | CXCR4, CXCL12, CXCR1 | CXCR4 1/4885KDM1A 4700/4885MAOB 3403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.