Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.52 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | HTR6 | P50406 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
| ▸ | HTR3B | O95264 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL4794093 | 0.97 | HTR2C (0.56) | HTR2CROCK2ROCK1PKN2CYP1A2 | |
| SCHEMBL12215244 | 0.81 | HTR2C (0.59) | HTR2CROCK2ROCK1PKN2CYP1A2 | |
| SCHEMBL6092156 | 0.81 | HTR2C (0.59) | HTR2CROCK2ROCK1PKN2CYP1A2 | |
| SCHEMBL1486973 | 0.81 | HTR2C (0.59) | HTR2CROCK2ROCK1PKN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL6101642 | 0.80 | HTR2C (0.57) | HTR2CROCK2ROCK1PKN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL3684027 | 0.80 | HTR2C (0.57) | HTR2CROCK2ROCK1PKN2CYP1A2 | |
| SCHEMBL4763791 | 0.79 | ABCG2 (0.40) | HTR2CMAPTHTR3EHTR3BHTR3A | |
| SCHEMBL4763429 | 0.78 | SMN1; SMN2 (0.53) | CYP1A2CYP3A4MAPTLMNACYP2D6 | |
| SCHEMBL20009340 | 0.78 | HTR2C (0.55) | HTR2CROCK2ROCK1PKN2CYP1A2 | |
| SCHEMBL30744781 | 0.77 | HTR2C (0.54) | HTR2CROCK2ROCK1PKN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1890228-B | Alpha-amino acid derivatives and their use as medicaments | MITSUBISHI TANABE PHARMA CORP | 2011-07-20 | — | — | CN | disclosed |
| US-7504423-B2 | α-amino acid derivatives and use thereof as medicines | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-03-17 | — | — | US | disclosed |
| US-20070049619-A1 | Alpha-amino acid derivatives and use thereof as medicines | MITSUBISHI PHAMA CORPORATION (JP) | 2007-03-01 | — | — | US | disclosed |
| EP-1695969-A1 | ALPHA-AMINO ACID DERIVATIVES AND USE THEREOF AS MEDICINES | Mitsubishi Pharma Corporation (JP) | 2006-08-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049619-A1 | Alpha-amino acid derivatives and use thereof as medicines | DPP4, DPP7, DPP3 | HTR2C 2499/4885ROCK2 4198/4885ROCK1 3740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.