Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 3/20 | 0.42 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28247572 | 0.83 | HTR2A (0.43) | HTR2AHTR2CHTR2BTAAR1KDM1A | |
| SCHEMBL28064118 | 0.77 | HTR2A (0.39) | HTR2AHTR2CHTR2BTAAR1KDM1A | |
| SCHEMBL777518 | 0.77 | HTR2A (0.39) | HTR2AHTR2CHTR2BTAAR1KDM1A | |
| SCHEMBL16877131 | 0.77 | HTR2A (0.39) | HTR2AHTR2CHTR2BTAAR1KDM1A | |
| SCHEMBL29447418 | 0.76 | HTR2A (0.44) | HTR2AHTR2CHTR2BTAAR1KDM1A | |
| SCHEMBL24950120 | 0.75 | TAAR1 (0.48) | HTR2AHTR2CHTR2BTAAR1KDM1A | |
| SCHEMBL29878889 | 0.74 | HTR2C (0.47) | HTR2AHTR2CHTR2BTAAR1KDM1A | |
| SCHEMBL1515236 | 0.74 | HTR2C (0.47) | HTR2AHTR2CHTR2BTAAR1KDM1A | |
| SCHEMBL4071919 | 0.74 | TAAR1 (0.39) | HTR2AHTR2CHTR2BTAAR1KDM1A | |
| SCHEMBL16879137 | 0.74 | SLC6A2 (0.38) | HTR2AHTR2CHTR2BTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101626686-A | 3-substituent-1, 2, 3-benzotriazinone compounds for improving glutaminic synaptic responses | CORTEX PHARMA INC | 2010-01-13 | — | — | CN | claimed |
| CN-109589325-B | A kind of pharmaceutical composition and preparation method thereof for treating enteritis | 牡丹江医学院 | 2019-11-26 | — | — | CN | disclosed |
| CN-109589325-A | A kind of pharmaceutical composition and preparation method thereof for treating enteritis | 牡丹江医学院 | 2019-04-09 | — | — | CN | disclosed |
| CN-101626686-A | 3-substituent-1, 2, 3-benzotriazinone compounds for improving glutaminic synaptic responses | CORTEX PHARMA INC | 2010-01-13 | — | — | CN | disclosed |
| EP-1415986-B1 | SPIRO ISOBENZOFURANES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | BANYU PHARMA CO LTD (JP) | 2009-04-08 | — | — | EP | disclosed |
| US-7205417-B2 | Spiro compounds | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |
| CN-1538956-A | Spiro compounds | ������ҩ��ʽ���� | 2004-10-20 | — | — | CN | disclosed |
| US-5714503-A | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 1998-02-03 | — | — | US | disclosed |