Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ASF1A | Q9Y294 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13569076 | 1.00 | MAPT (0.53) | MAPTSMN1; SMN2ASF1AKMT2AMEN1 | |
| SCHEMBL13568976 | 0.95 | MAPT (0.49) | MAPTSMN1; SMN2ASF1AKMT2AMEN1 | |
| SCHEMBL4075244 | 0.94 | MAPT (0.50) | MAPTSMN1; SMN2ASF1AKMT2AMEN1 | |
| SCHEMBL4071500 | 0.92 | MAPT (0.64) | MAPTSMN1; SMN2ASF1AKMT2AMEN1 | |
| SCHEMBL13568905 | 0.92 | MAPT (0.64) | MAPTSMN1; SMN2ASF1AKMT2AMEN1 | |
| SCHEMBL6119459 | 0.91 | ASF1A (0.47) | MAPTSMN1; SMN2ASF1AKMT2AMEN1 | |
| SCHEMBL6119480 | 0.91 | ASF1A (0.47) | MAPTSMN1; SMN2ASF1AKMT2AMEN1 | |
| SCHEMBL27937023 | 0.90 | ASF1A (0.51) | MAPTSMN1; SMN2ASF1AKMT2AMEN1 | |
| SCHEMBL13568986 | 0.89 | MAPT (0.63) | MAPTSMN1; SMN2ASF1AKMT2AMEN1 | |
| SCHEMBL13568931 | 0.89 | MIF (0.57) | MAPTSMN1; SMN2KMT2AMEN1MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |