Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 4/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4074607 | 0.92 | CXCR4 (0.38) | CXCR4OPRM1OPRL1 | |
| SCHEMBL4069578 | 0.91 | CXCR4 (0.42) | CXCR4OPRM1OPRL1 | |
| SCHEMBL2626917 | 0.89 | CXCR4 (0.40) | CXCR4OPRM1OPRL1 | |
| SCHEMBL4074228 | 0.88 | CXCR4 (0.39) | CXCR4OPRM1OPRL1 | |
| SCHEMBL4071754 | 0.87 | CXCR4 (0.39) | CXCR4 | |
| SCHEMBL4067087 | 0.87 | CXCR4 (0.39) | CXCR4 | |
| SCHEMBL4073881 | 0.87 | CXCR4 (0.39) | CXCR4 | |
| SCHEMBL4076897 | 0.86 | CXCR4 (0.38) | CXCR4 | |
| SCHEMBL4067105 | 0.86 | CXCR4 (0.40) | CXCR4 | |
| SCHEMBL4067109 | 0.86 | CXCR4 (0.40) | CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2055705-A1 | COMPOUND HAVING CYCLIC GROUP BOUND THERETO THROUGH SPIRO BINDING AND USE THEREOF | Ono Pharmaceutical CO., LTD. (JP) | 2009-05-06 | — | — | EP | disclosed |