Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 12/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 10/20 | 0.44 |
| ▸ | MELK | Q14680 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4074742 | 1.00 | KCNH2 (0.44) | KCNH2MCHR1MELKOPRM1OPRK1 | |
| SCHEMBL4074749 | 0.87 | MCHR1 (0.49) | KCNH2MCHR1 | |
| SCHEMBL13664939 | 0.85 | MCHR1 (0.57) | KCNH2MCHR1AVPR1A | |
| SCHEMBL4076927 | 0.80 | MCHR1 (0.53) | KCNH2MCHR1AVPR1A | |
| SCHEMBL4076908 | 0.80 | MCHR1 (0.53) | KCNH2MCHR1AVPR1A | |
| SCHEMBL4076904 | 0.80 | MCHR1 (0.53) | KCNH2MCHR1AVPR1A | |
| SCHEMBL13664942 | 0.76 | MCHR1 (0.64) | KCNH2MCHR1AVPR1A | |
| SCHEMBL4076079 | 0.76 | MCHR1 (0.64) | KCNH2MCHR1OPRM1OPRK1AVPR1A | |
| SCHEMBL4252556 | 0.76 | MCHR1 (0.64) | KCNH2MCHR1OPRM1OPRK1AVPR1A | |
| SCHEMBL13664934 | 0.75 | MCHR1 (0.60) | KCNH2MCHR1OPRM1AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072519-A1 | DIARYL KETIMINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-06-24 | — | — | EP | disclosed |