Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075313 | 0.88 | TP53 (0.39) | KDM4EKMT2ATP53THRBS1PR1 | |
| SCHEMBL4078988 | 0.70 | GAA (0.55) | KDM4EKMT2AATMGAAMEN1 | |
| SCHEMBL4079104 | 0.68 | IDH1 (0.38) | KMT2AGAAMEN1MAPT | |
| SCHEMBL6291931 | 0.68 | GSK3B (0.89) | GSK3B | |
| SCHEMBL250688 | 0.66 | GSK3B (1.00) | GSK3BALDH1A1MAPT | |
| SCHEMBL3971702 | 0.65 | PIK3CD (0.38) | KDM4EKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL4086084 | 0.64 | PIK3CD (0.38) | KDM4EKMT2AGAAMEN1MAPT | |
| SCHEMBL4077257 | 0.64 | PIK3CD (0.39) | KMT2AGAAMEN1MAPT | |
| SCHEMBL3167651 | 0.62 | KMT2A (0.45) | KDM4EKMT2AATMGAAMEN1 | |
| SCHEMBL3167662 | 0.62 | KMT2A (0.45) | KDM4EKMT2AATMGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054410-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | Wyeth (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008021331-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | disclosed |