Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 6/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4081499 | 0.95 | AR (0.47) | ARMEN1KMT2AMAPTGAA | |
| SCHEMBL4508808 | 0.95 | AR (0.47) | ARMEN1KMT2AMAPTGAA | |
| SCHEMBL4077593 | 0.95 | AR (0.47) | ARMEN1KMT2AMAPTGAA | |
| SCHEMBL4079469 | 0.92 | CA1 (0.45) | MEN1KMT2AMAPTIDH1CA1 | |
| SCHEMBL4078937 | 0.85 | AR (0.49) | ARMEN1KMT2AMAPTGAA | |
| SCHEMBL4078206 | 0.83 | GAA (0.51) | ARMEN1KMT2AMAPTGAA | |
| SCHEMBL4079139 | 0.83 | GAA (0.51) | ARMEN1KMT2AMAPTGAA | |
| SCHEMBL4084130 | 0.81 | CA1 (0.47) | MEN1KMT2AMAPTIDH1CA1 | |
| SCHEMBL4078711 | 0.81 | GAA (0.49) | ARMEN1KMT2AMAPTGAA | |
| SCHEMBL4082583 | 0.81 | GAA (0.49) | ARMEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054410-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | Wyeth (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008021331-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | disclosed |