Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 20/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3965324 | 0.91 | ACP1 (0.45) | ACP1 | |
| SCHEMBL4075734 | 0.87 | ACP1 (0.45) | ACP1 | |
| Hydrochloric Acid SCHEMBL4071535 | 0.85 | HRH4 (0.36) | — | |
| SCHEMBL3958520 | 0.82 | TYRO3 (0.43) | ACP1 | |
| Hydrochloric Acid SCHEMBL4089904 | 0.82 | ACP1 (0.44) | ACP1 | |
| SCHEMBL4084390 | 0.80 | AURKA (0.39) | ACP1 | |
| SCHEMBL3961626 | 0.80 | MERTK (0.36) | ACP1 | |
| Hydrochloric Acid SCHEMBL4084777 | 0.78 | TYRO3 (0.40) | — | |
| Hydrochloric Acid SCHEMBL4069332 | 0.77 | GSK3A (0.35) | — | |
| SCHEMBL3961594 | 0.77 | TYRO3 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1989200-B1 | [4-(BENZO[B]THIOPHEN-2-YL)-PYRIMIDIN-2-YL]-AMINE DERIVATIVES AS IKK-BETA INHIBITORS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASES | LILLY CO ELI (US) | 2009-07-29 | — | — | EP | disclosed |