Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 17/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1095573 | 0.85 | CASR (0.46) | CASR | |
| Hydrochloric Acid SCHEMBL1096079 | 0.84 | CASR (0.47) | CASR | |
| SCHEMBL4076033 | 0.82 | CASR (0.45) | CASRTTR | |
| SCHEMBL1095964 | 0.79 | CASR (0.43) | CASRTTR | |
| SCHEMBL4079728 | 0.77 | CASR (0.44) | CASRTTR | |
| SCHEMBL1095909 | 0.77 | CASR (0.44) | CASRTTR | |
| SCHEMBL1095449 | 0.73 | TTR (0.40) | CASRTTR | |
| SCHEMBL1105824 | 0.72 | CASR (0.48) | CASRCYP2D6 | |
| SCHEMBL1105849 | 0.72 | CASR (0.49) | CASRCYP2D6 | |
| SCHEMBL1105995 | 0.72 | CASR (0.45) | CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2085383-A1 | PIPERIDINE DERIVATIVES OR SALTS THEREOF | Astellas Pharma Inc. (JP) | 2009-08-05 | — | — | EP | claimed |