Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 14/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4076044 | 1.00 | MCHR1 (0.60) | MCHR1KCNH2SIGMAR1ADRA1A | |
| SCHEMBL1003284 | 0.85 | MCHR1 (0.66) | MCHR1KCNH2 | |
| SCHEMBL4314869 | 0.85 | MCHR1 (0.76) | MCHR1KCNH2SIGMAR1ADRA1A | |
| SCHEMBL4314871 | 0.85 | MCHR1 (0.76) | MCHR1KCNH2SIGMAR1ADRA1A | |
| SCHEMBL13664927 | 0.84 | MCHR1 (0.84) | MCHR1KCNH2SIGMAR1 | |
| SCHEMBL4072347 | 0.81 | MCHR1 (0.76) | MCHR1KCNH2ADRA1A | |
| SCHEMBL13668374 | 0.77 | MCHR1 (0.77) | MCHR1KCNH2SIGMAR1ADRA1A | |
| SCHEMBL4076051 | 0.76 | MCHR1 (0.53) | MCHR1KCNH2 | |
| SCHEMBL1002597 | 0.75 | MCHR1 (0.77) | MCHR1KCNH2SIGMAR1 | |
| SCHEMBL4066849 | 0.75 | MCHR1 (1.00) | MCHR1KCNH2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072519-A1 | DIARYL KETIMINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-06-24 | — | — | EP | disclosed |