Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 12/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 10/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29357392 | 1.00 | SIRT2 (0.49) | SIRT2SIRT1RAB9ATDP1SIRT3 | |
| SCHEMBL4727432 | 1.00 | SIRT2 (0.49) | SIRT2SIRT1RAB9ATDP1SIRT3 | |
| SCHEMBL10727549 | 0.98 | SIRT2 (0.50) | SIRT2SIRT1RAB9ATDP1SIRT3 | |
| Hydrochloric Acid SCHEMBL380911 | 0.98 | SIRT2 (0.49) | SIRT2SIRT1RAB9ATDP1SIRT3 | |
| SCHEMBL1842451 | 0.97 | SIRT2 (0.46) | SIRT2SIRT1RAB9ATDP1SIRT3 | |
| SCHEMBL29374941 | 0.97 | SIRT2 (0.46) | SIRT2SIRT1RAB9ATDP1SIRT3 | |
| SCHEMBL31045803 | 0.97 | SIRT2 (0.51) | SIRT2SIRT1RAB9ASIRT3 | |
| SCHEMBL30070668 | 0.97 | SIRT2 (0.48) | SIRT2SIRT1RAB9ATDP1SIRT3 | |
| Hydrochloric Acid SCHEMBL31754825 | 0.96 | SIRT2 (0.46) | SIRT2SIRT1RAB9ATDP1SIRT3 | |
| Hydrochloric Acid SCHEMBL1723683 | 0.96 | SIRT2 (0.46) | SIRT2SIRT1RAB9ATDP1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101907614-B | Method for screening cathepsin B inhibitor by combining ultra-performance liquid chromatography and mass spectrometry | CHANGCHUN APPLIED CHEMISTRY | 2012-05-23 | — | — | CN | claimed |
| CN-101907614-A | Method for screening cathepsin B inhibitor by adopting ultra performance liquid chromatography and mass spectrometry | CHANGCHUN APPLIED CHEMISTRY | 2010-12-08 | — | — | CN | claimed |
| CN-101907614-B | Method for screening cathepsin B inhibitor by combining ultra-performance liquid chromatography and mass spectrometry | CHANGCHUN APPLIED CHEMISTRY | 2012-05-23 | — | — | CN | disclosed |
| CN-101907614-A | Method for screening cathepsin B inhibitor by adopting ultra performance liquid chromatography and mass spectrometry | CHANGCHUN APPLIED CHEMISTRY | 2010-12-08 | — | — | CN | disclosed |
| EP-1827478-A4 | METHODS OF TREATMENT FOR INJURED OR DISEASED JOINTS | MUCOSAL THERAPEUTICS LLC (US) | 2009-08-05 | — | — | EP | disclosed |
| US-20080139458-A1 | Lubricating a joint in a mammal by administering lubricin and an enzyme inhibitor like Z-Leu-Leu-Leu-fluoromethyl ketone (Z-LLL-FMK) | MUCOSAL THERAPEUTICS | 2008-06-12 | — | — | US | disclosed |
| EP-1827478-A2 | METHODS OF TREATMENT FOR INJURED OR DISEASED JOINTS | Mucosal Therapeutics LLC (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006060473-A2 | METHODS OF TREATMENT OF INJURED OR DISEASED JOINTS WITH LUBRICIN COMPOSITIONS | MUCOSAL THERAPEUTICS LLC (US) | 2006-06-08 | — | — | WO | disclosed |