Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 2/20 | 0.85 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PDE2A | O00408 | 1/20 | 0.54 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25640 | 0.92 | PTPN7 (1.00) | PTPN7ALOX15MEN1KMT2AKDM4E | |
| SCHEMBL29367022 | 0.92 | PTPN7 (1.00) | PTPN7ALOX15MEN1KMT2AKDM4E | |
| SCHEMBL15201762 | 0.90 | PTPN7 (0.96) | PTPN7ALOX15MEN1KMT2AKDM4E | |
| SCHEMBL10299391 | 0.90 | PTPN7 (0.71) | PTPN7ALOX15MEN1KMT2AKDM4E | |
| SCHEMBL9714119 | 0.90 | PTPN7 (0.71) | PTPN7ALOX15MEN1KMT2AKDM4E | |
| SCHEMBL10902015 | 0.90 | PTPN7 (0.89) | PTPN7ALOX15MEN1KMT2AKDM4E | |
| SCHEMBL15201765 | 0.90 | PTPN7 (0.96) | PTPN7ALOX15MEN1KMT2AKDM4E | |
| SCHEMBL23832447 | 0.89 | PTPN7 (0.69) | PTPN7ALOX15MEN1KMT2AKDM4E | |
| SCHEMBL7422807 | 0.89 | PTPN7 (0.69) | PTPN7ALOX15MEN1KMT2AKDM4E | |
| SCHEMBL29843499 | 0.89 | PTPN7 (0.69) | PTPN7ALOX15MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |