Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 19/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4077400 | 0.86 | MEN1 (0.54) | GRM5 | |
| SCHEMBL4078853 | 0.84 | GRM5 (0.64) | GRM5 | |
| SCHEMBL4071774 | 0.83 | GRM5 (0.78) | GRM5 | |
| SCHEMBL1821580 | 0.82 | GRM5 (1.00) | GRM5 | |
| SCHEMBL30879625 | 0.82 | GRM5 (1.00) | GRM5 | |
| SCHEMBL30255585 | 0.82 | GRM5 (1.00) | GRM5 | |
| SCHEMBL4070164 | 0.82 | GRM5 (1.00) | GRM5 | |
| SCHEMBL4069253 | 0.82 | GRM5 (1.00) | GRM5 | |
| SCHEMBL18669027 | 0.81 | GRM5 (0.50) | GRM5 | |
| SCHEMBL4069645 | 0.81 | GRM5 (0.70) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507836-B2 | Benzamide modulators of metabotropic glutamate receptors | MERCK & CO. INC. (US) | 2009-03-24 | — | — | US | claimed |