Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 10/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.43 |
| ▸ | PDE6D | O43924 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565592 | 0.91 | SLC29A1 (0.49) | SLC29A1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL15065643 | 0.85 | SLC29A1 (0.48) | SLC29A1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL141541 | 0.84 | SLC29A1 (0.54) | SLC29A1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL3395769 | 0.84 | SLC29A1 (0.54) | SLC29A1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL11026413 | 0.82 | SLC29A1 (0.41) | SLC29A1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL11023583 | 0.82 | SLC29A1 (0.41) | SLC29A1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL1956785 | 0.79 | SLC29A1 (0.41) | SLC29A1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL7446838 | 0.76 | SLC29A1 (0.47) | SLC29A1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL10665575 | 0.76 | HIF1A (0.34) | MAPTKDM4ELMNASMN1; SMN2TSHR | |
| SCHEMBL10663473 | 0.75 | KDM4E (0.40) | SLC29A1KDM4ELMNASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2062580-A1 | Use of dipyridamole or mopidamole for treatment and prevention of thromboembolic diseases and disorders caused by excessive formation of thrombin and/or by elevated expression of trombin receptors | Boehringer Ingelheim International GmbH (DE) | 2009-05-27 | — | — | EP | disclosed |