Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | MEN1 | O00255 | 8/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 10/20 | 0.53 |
| ▸ | NPC1 | O15118 | 9/20 | 0.53 |
| ▸ | STAT1 | P42224 | 1/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3523965 | 0.82 | MAPT (0.64) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL3976858 | 0.77 | NPC1 (0.56) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL13192815 | 0.77 | MAPT (0.59) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL4075234 | 0.77 | MEN1 (0.68) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL10352100 | 0.76 | MAPT (0.67) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL14468806 | 0.75 | MAPT (0.77) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL10352099 | 0.75 | MAPT (0.65) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL4487938 | 0.74 | GAA (0.61) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL2255388 | 0.74 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL8171460 | 0.73 | MAPT (0.74) | MAPTALDH1A1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054410-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | Wyeth (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008021331-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | disclosed |