SCHEMBL4078788

SCHEMBL4078788

CC(C)CC=C(O)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.48
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
RNPEP Q9H4A4 1/20 0.32
SLC7A5 Q01650 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL669944 1.00 GRIK1 (0.48) GRIK1CYP2D6CYP2C19RNPEPSLC7A5
SCHEMBL11803921 0.80 GRIK1 (0.33) GRIK1
SCHEMBL1409891 0.79 GRIK1 (0.48) GRIK1CYP2D6CYP2C19RNPEPSLC7A5
SCHEMBL23250 0.77 GRIK1 (0.47) GRIK1CYP2D6CYP2C19RNPEPSLC7A5
SCHEMBL23252 0.77 GRIK1 (0.47) GRIK1CYP2D6CYP2C19RNPEPSLC7A5
SCHEMBL27582592 0.77 GRIK1 (0.39) GRIK1CYP2D6CYP2C19ALDH1A1
SCHEMBL16012 0.75 GRIK1 (0.46) GRIK1CYP2D6CYP2C19RNPEPSLC7A5
Hydrochloric Acid SCHEMBL38657492 0.75 GRIK1 (0.46) GRIK1CYP2D6CYP2C19RNPEPSLC7A5
SCHEMBL6544850 0.75 GRIK1 (0.50) GRIK1CYP2D6CYP2C19RNPEPSLC7A5
SCHEMBL9419761 0.75 GRIK1 (0.46) GRIK1CYP2D6CYP2C19RNPEPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8664350-B2 Polymeric coupling agents LUBRIZOL LIMITED (GB) 2014-03-04 US claimed
EP-2084219-B1 POLYMERIC COUPLING AGENTS LUBRIZOL LTD (GB) 2012-09-05 EP claimed
US-20090306252-A1 Polymeric Coupling Agents LUBRIZOL LIMITED (GB) 2009-12-10 US claimed
EP-2084219-A1 POLYMERIC COUPLING AGENTS Lubrizol Limited (GB) 2009-08-05 EP claimed
WO-2008049840-A1 POLYMERIC COUPLING AGENTS LUBRIZOL LIMITED (GB) 2008-05-02 WO claimed
EP-0474452-B1 Thermal transfer dye image receiving sheet NEW OJI PAPER CO LTD (JP) 1995-07-12 EP claimed
CN-107922442-B Organosilicon compounds having (meth) acrylate groups and method for producing the same 瓦克化学股份公司 2020-07-03 CN disclosed
EP-3344634-B1 ORGANOSILICON COMPOUNDS HAVING (METH)ACRYLATE GROUPS AND A PROCESS FOR PREPARATION THEREOF WACKER CHEMIE AG (DE) 2019-10-02 EP disclosed
EP-3344634-A1 ORGANOSILICON COMPOUNDS HAVING (METH)ACRYLATE GROUPS AND A PROCESS FOR PREPARATION THEREOF Wacker Chemie AG (DE) 2018-07-11 EP disclosed
WO-2017036743-A1 ORGANOSILICON COMPOUNDS HAVING (METH)ACRYLATE GROUPS AND A PROCESS FOR PREPARATION THEREOF WACKER CHEMIE AG (DE) 2017-03-09 WO disclosed
US-8664350-B2 Polymeric coupling agents LUBRIZOL LIMITED (GB) 2014-03-04 US disclosed
EP-2084219-B1 POLYMERIC COUPLING AGENTS LUBRIZOL LTD (GB) 2012-09-05 EP disclosed
US-20090306252-A1 Polymeric Coupling Agents LUBRIZOL LIMITED (GB) 2009-12-10 US disclosed
EP-2084219-A1 POLYMERIC COUPLING AGENTS Lubrizol Limited (GB) 2009-08-05 EP disclosed
WO-2008049840-A1 POLYMERIC COUPLING AGENTS LUBRIZOL LIMITED (GB) 2008-05-02 WO disclosed
US-5973094-A Functional polymers WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1999-10-26 US disclosed
EP-0794199-A2 Novel functional polymers WAKO PURE CHEMICAL INDUSTRIES, LTD (JP) 1997-09-10 EP disclosed
US-4961750-A Acrylate tanning agent ROHM GMBH (DE) 1990-10-09 US disclosed