Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 9/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4076677 | 1.00 | MAPT (0.54) | MAPTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL3863102 | 1.00 | MAPT (0.54) | MAPTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL3972543 | 0.90 | MAPT (0.56) | MAPTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL4500517 | 0.90 | MAPT (0.56) | MAPTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL4075123 | 0.90 | MAPT (0.56) | MAPTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL3170512 | 0.82 | MAPT (0.59) | MAPTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL4075012 | 0.82 | MAPT (0.59) | MAPTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL4077819 | 0.82 | MAPT (0.59) | MAPTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL4078193 | 0.81 | MAPT (0.52) | MAPTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL4078208 | 0.79 | MAPT (0.59) | MAPTKMT2AMEN1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054410-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | Wyeth (US) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008021331-A2 | OXAZOLIDONE DERIVATIVES AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | disclosed |