Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 10/20 | 0.40 |
| ▸ | APOB | P04114 | 9/20 | 0.40 |
| ▸ | SMO | Q99835 | 8/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CFD | P00746 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5298934 | 0.90 | SMO (0.43) | MTTPAPOBSMOCFDKLK7 | |
| SCHEMBL4079252 | 0.88 | MTTP (0.40) | MTTPAPOBSMONPC1RAB9A | |
| SCHEMBL3289783 | 0.84 | SMO (0.46) | MTTPAPOBSMONPC1RAB9A | |
| SCHEMBL3289751 | 0.83 | NAMPT (0.46) | MTTPAPOBSMONPC1RAB9A | |
| SCHEMBL3293823 | 0.82 | NTRK1 (0.44) | MTTPAPOBSMONPC1RAB9A | |
| SCHEMBL3288633 | 0.82 | EPHX2 (0.48) | MTTPAPOBSMONPC1RAB9A | |
| SCHEMBL3288774 | 0.82 | MTTP (0.44) | MTTPAPOBSMONPC1RAB9A | |
| SCHEMBL13360719 | 0.82 | MTTP (0.42) | MTTPAPOBSMONPC1RAB9A | |
| SCHEMBL3289661 | 0.81 | SMO (0.44) | MTTPAPOBSMONPC1RAB9A | |
| SCHEMBL3288902 | 0.81 | EPHX1 (0.46) | MTTPAPOBSMONPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753721-B1 | AROYL-O-PIPERIDINE DERIVATIVES FOR THE TREATMENT OF DIABETES-RELATED PROBLEMS | MERCK PATENT GMBH (DE) | 2009-08-05 | — | — | EP | disclosed |