Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL393754 | 0.88 | AKT1 (1.00) | AKT1MTOR | |
| SCHEMBL18434073 | 0.88 | AKT1 (1.00) | AKT1MTOR | |
| SCHEMBL289851 | 0.88 | AKT1 (1.00) | AKT1MTOR | |
| SCHEMBL2901002 | 0.85 | MTOR (1.00) | AKT1MTOR | |
| SCHEMBL26062596 | 0.85 | MTOR (1.00) | AKT1MTOR | |
| SCHEMBL2903023 | 0.85 | MTOR (1.00) | AKT1MTOR | |
| SCHEMBL10224929 | 0.84 | MTOR (1.00) | AKT1MTOR | |
| SCHEMBL18434394 | 0.83 | MTOR (1.00) | AKT1MTOR | |
| SCHEMBL392022 | 0.83 | MTOR (1.00) | AKT1MTOR | |
| SCHEMBL392021 | 0.83 | MTOR (1.00) | AKT1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057156-A1 | 2-METHYLMORPHOLINE PYRIDO-, PYRAZO- AND PYRIMIDO-PYRIMIDINE DERIVATIVES AS MTOR INHIBITORS | Kudos Pharmaceuticals Limited (GB) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008023161-A1 | 2-METHYLMORPHOLINE PYRIDO-, PYRAZO- AND PYRIMIDO-PYRIMIDINE DERIVATIVES AS MTOR INHIBITORS | KUDOS PHARMACEUTICALS LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |