SCHEMBL4081023

SCHEMBL4081023

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nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9690679 1.00 GAA (0.33) GAA
SCHEMBL27812014 1.00 GAA (0.33) GAA
SCHEMBL28082294 0.94 GAA (0.30) GAA
Fluoride Ion SCHEMBL28101087 0.92
SCHEMBL4268176 0.90 PDE4A (0.32) GAA
SCHEMBL27687926 0.90 PDE4A (0.32) GAA
SCHEMBL28294147 0.90 PDE4A (0.32) GAA
SCHEMBL9494454 0.90 PDE4A (0.32) GAA
SCHEMBL28861302 0.89 GAA (0.38) GAA
SCHEMBL4942263 0.82 GAA (0.35) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7528115-B2 Carbonate and carbamate prodrugs of thiazolo[4,5-d]pyrimidines ANADYS PHARMACEUTICALS, INC. (US) 2009-05-05 US disclosed
US-20080020989-A1 CARBONATE AND CARBAMATE PRODRUGS OF THIAZOLO[4,5-d]PYRIMIDINES ANADYS PHARMACEUTICALS, INC. (US) 2008-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080020989-A1 CARBONATE AND CARBAMATE PRODRUGS OF THIAZOLO[4,5-d]PYRIMIDINES TYMP, TYMS, DCTD GAA 1540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.