Phenylalanine

Phenylalanine

SCHEMBL4081350

N[C@@H](Cc1ccccc1)C(=O)O.Nc1ccc2ccccc2c1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.67
ALPI P09923 1/20 0.67
PKM P14618 1/20 0.67
PTGS1 P23219 1/20 0.67
XIAP P98170 1/20 0.67
TPH1 P17752 7/20 0.53
PPARG P37231 1/20 0.52
PPARA Q07869 1/20 0.52
ALDH1A1 P00352 1/20 0.52
CYP3A4 P08684 1/20 0.52
HSD17B10 Q99714 1/20 0.52
SLC1A3 P43003 1/20 0.50
SLC1A2 P43004 1/20 0.50
SLC1A1 P43005 1/20 0.50
GRIA2 P42262 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Phenylalanine SCHEMBL4081344 1.00 SLC7A5 (0.67) SLC7A5ALPIPKMPTGS1XIAP
Tyrosine SCHEMBL28637490 0.92 SLC7A5 (0.65) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL27785427 0.88 SLC7A5 (0.71) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL27502165 0.87 SLC7A5 (0.88) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL8185410 0.87 PPARG (0.50) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL14780599 0.86 SLC7A5 (0.58) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL15348826 0.85 SLC7A5 (0.85) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL1507753 0.85 SLC7A5 (0.85) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL29375097 0.84 SLC7A5 (0.65) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL93304 0.84 SLC7A5 (0.65) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3206723-A1 BIOLOGICAL INDICATOR American Sterilizer Company (US) 2017-08-23 EP claimed
WO-2016060714-A1 BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY (US) 2016-04-21 WO claimed
EP-2084294-A2 STERILIZATION INDICATOR American Sterilizer Company (US) 2009-08-05 EP claimed
EP-2084293-A2 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR American Sterilizer Company (US) 2009-08-05 EP claimed
WO-2008082728-A2 STERILIZATION INDICATOR AMERICAN STERILIZER COMPANY (US) 2008-07-10 WO claimed
WO-2008079469-A2 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY (US) 2008-07-03 WO claimed
EP-2658990-A2 ARTICLES AND METHOD FOR DETECTING A TARGET MICROORGANISM 3M Innovative Properties Company (US) 2013-11-06 EP disclosed
WO-2012092181-A2 ARTICLES AND METHOD FOR DETECTING A TARGET MICROORGANISM 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-07-05 WO disclosed